USP30 (scissors) is an enzyme that plays a role in the regulation of cellular processes through the removal of ubiquitin molecules from target proteins.

Mitochondria (green structure) is an important part of the cellular network in your body. As cells in your body age, mitochondria grow tags. These tags are removed by USP30. A healthy person naturally produces and regulates USP30. With age and disease, USP30 activity increases excessively leading to too many tags being cut. If USP30 isn’t regulated properly then too many tags are cut leading to cell death and neuroinflammation.

This build up of dead cells and neuroinflammation may lead to Alzheimer’s disease, Parkinson’s disease or ALS (Amyotrophic lateral sclerosis)